The SIM1 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to SIM1. This antibody recognizes Human, and Drosophila/Arthropod antigen. The SIM1 Antibody (N-term) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
SIM1 and SIM2 genes are Drosophila single-minded (sim)
gene homologs. SIM1 transcript was detected only in fetal kidney
out of various adult and fetal tissues tested. Since the sim gene
plays an important role in Drosophila development and has peak
levels of expression during the period of neurogenesis,it was
proposed that the human SIM gene is a candidate for involvement in
certain dysmorphic features (particularly the facial and skull
characteristics), abnormalities of brain development, and/or mental
retardation of Down syndrome